Ultracet is a unique pain medication. It is used to relieve moderate, acute pain such as pain following surgical procedures, including dental surgery. Ultracet may be used for other types of pain as determined by your health care provider.
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The mode of action of tramadol has yet to be fully understood,
but it is believed to work through modulation of the GABAergic,
noradrenergic and serotonergic systems, in addition to its mild
agonism of the ?-opioid receptor. The contribution of non-opioid
activity is demonstrated by the analgesic effects of tramadol not
being fully antagonised by the ?-opioid receptor antagonist naloxone.
Tramadol is used to treat moderate and severe pain and most types
of neuralgia, including trigeminal neuralgia.[citation needed] It
has been suggested that tramadol could be effective for alleviating
symptoms of depression and anxiety because of its action on GABAergic,
noradrenergic and specifically serotonergic systems. However, health
professionals have not yet endorsed its use on a large scale for
disorders such as this. Oral doses range from 50–600 mg daily, with
up to 400 mg daily when given IV/IM. The formulation containing
APAP contains 37.5 mg of tramadol and 325 mg of paracetamol, intended
for oral administration with a common dosing recommendation of one
or two tabs every four to six hours
Side effects that you should report to your prescriber or health care professional as soon as possible:
Rare or uncommon: changes in vision; difficulty breathing, shortness of breath; fast or irregular heartbeat; hallucinations (seeing and hearing things that are not really there); not passing urine as often as usual; redness, blistering, peeling or loosening of the skin, including inside the mouth; skin rash, itching; seizures (convulsions); yellow tint to your skin or whites of your eyes.
More common: anxiety, agitation; vomiting.
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome); constipation or diarrhea; difficulty sleeping; dizziness, drowsiness; dry mouth; false sense of well being, feeling of unreality, mood changes; headache; indigestion; itching; nausea; sweating or flushing.
Tramadol and acetaminophen has not been studied in pregnant women. However, studies in animals have shown that tramadol and acetaminophen causes birth defects and other problems. Before taking Ultracet, make sure your doctor knows if you are pregnant or if you may become pregnant.
ULTRACET® is a combination product. The clinical presentation of overdose may include the signs and symptoms of tramadol toxicity, acetaminophen toxicity or both. The initial symptoms of tramadol overdosage may include respiratory depression and or seizures. The initial symptoms seen within the first 24 hours following an acetaminophen overdose are: anorexia, nausea, vomiting, malaise, pallor and diaphoresis.
ULTRACET® may impair mental or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery.
ULTRACET should not be taken with alcohol containing beverages.